International Research Journal of Education and Technology

With its ambiguous clinical symptoms and absence of a definitive diagnostic technique, scrub typhus is commonly misdiagnosed. Fever, rash, and eschar are common symptoms that require test confirmation. Pneumonitis and/or ARDS should be considered differential diagnoses in patients with acute febrile sickness. A thorough search for eschar, especially in hidden areas, is helpful in diagnosis.

Eschar can be found in a small number of patients. The doctor should be informed of the limits of all currently available scrub typhus serological testing. Depending on the endemicster, a cutoff antibody titer of 1:10 to 1:400 is necessary for serological diagnosis.