International Research Journal of Education and Technology

The fish mucus was extracted from C. catla by using aqueous solution and the chemical composition showed 27.93% of protein, 5.9% of carbohydrate and 0.35% of lipids. The antibacterial activity of the mucus extract showed 17, 11, 14, 16, 11, 18, 12 and 13mm zone of inhibition at the highest concentration of 100µg/ml against S. aureus, K. pneumoniae, S. typhi, V. cholerae, E. coli, V. parahaemolyticus and S. pyogenes. The fish mucus observed MIC values of 100µg/ml against E. coli and the V. cholerae slightly arrested at the above concentration. The fish mucus showed the MBC values of 100µg/ml against E. coli and the V. cholerae slightly arrested at the same concentration. The anticancer activity of the fish mucus recorded 14.37 – 51.09% at 50 – 250µg/ml concentration against A549 cell line. Hence, above antibacterial and anticancer activity of the mucus recommended as good source of biological agent in future pharmacological industry. 

Keywords: Mucus; Biochemical; Antibacterial activity; MIC; MBC; Anticancer.