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| Current Approaches to Antibody Detection and Clinical Management of Chikungunya |
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Author Name Bernaitis L Jomol P J Arun K S Prejish C Anakha Vijayan Abstract Chikungunya, caused by the Chikungunya virus (CHIKV) and transmitted by Aedes mosquitoes, presents with acute febrile illness and severe joint pain, leading to substantial morbidity. Diagnosis involves various antibody detection methods such as ELISA and PRNT, complemented by molecular techniques like RT-PCR and clinical assessment. Management primarily consists of symptomatic relief and supportive care, including analgesics, hydration, rest, and vector control measures. Additionally, Siddha medicine offers potential herbal formulations for symptom alleviation, though its integration into mainstream healthcare awaits further validation. Efforts in Chikungunya management are bolstered by ongoing research into vaccines, antiviral therapies, and advanced diagnostic technologies like CRISPR-based assays. Despite the absence of specific antiviral treatments, accurate antibody detection and clinical management remain crucial in controlling outbreaks and mitigating the disease's impact. This review provides an overview of current methods for antibody detection and highlights strategies for clinical management, integrating recent advances and future directions. Future advancements hold promise for more effective interventions and enhanced disease control strategies, paving the way for better Chikungunya management and prevention in the years ahead. Keywords: Chikungunya, Antibody detection, Symptomatic treatment, Siddha medicine, Vector control, Diagnosis Published On : 2024-06-08 Article Download : 
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